Platelet-Rich Plasma (PRP) Injection

What is Platelet-Rich Plasma (PRP)?

Our blood consists of a liquid component known as plasma. It also consists of three main solid components which include the red blood cells (RBCs), white blood cells (WBCs), and platelets. Platelets play an important role in forming blood clots. They also consist of special proteins, known as growth factors, which help with our body’s healing process. Platelet-rich plasma or PRP is a high concentration of platelets and plasma. A normal blood specimen contains only 6% platelets, while platelet-rich plasma contains 94% of platelets and 5 to 10 times the concentration of growth factors found in normal blood, thus greater healing properties.

What are the Indications for PRP Injections?

PRP is a relatively new method of treatment for several orthopedic conditions such as muscle, ligament, and tendon injuries; arthritis; and fractures. PRP injections can help alleviate painful symptoms, promote healing, and delay joint replacement surgeries.

Platelet-Rich Plasma Injection Procedure  

Your doctor will first draw about 10 cc’s of blood from the large vein in your elbow. The blood is then spun in a centrifuge machine for about 10 to 15 minutes to separate the platelets from the remaining blood components. The injured part of your body is then anesthetized with a local anesthetic. The platelet-rich portion of your blood is then injected into your affected area. In some cases, your doctor may use ultrasound guidance for proper needle placement.

Post-Operative Care following PRP Injections

It is normal to feel some discomfort at the injection site for a few days after your procedure.

  • You will be prescribed pain medications by your doctor. 
  • You may use cold compresses to alleviate your symptoms. 
  • You will be instructed to stop any anti-inflammatory medications. 
  • You may resume your normal activities but should avoid any strenuous activities such as heavy lifting or exercises.

Risks and Complications of Platelet-Rich Plasma Injections

There are very minimal risks associated with PRP injections. Some of the potential risks include:

  • Increased pain at the injection site
  • Infection
  • Damage to adjacent nerves or tissues
  • Formation of scar tissue
  • Calcification at the injection site
  •  The American Board of Orthopaedic Surgery
  • Philadelphia University and Thomas Jefferson University - Home of Sidney Kimmel Medical College
  • The Naval Medical Center
  • University of Miami Hospital

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